It's a wide-ranging conversation that covers his intellectual development as an economist, particularly his growing disillusionment with it as a graduate student and a young academic in the late 1960s and early 1970s. He makes the case that economics has changed a lot since that time and for the better.
Unfortunately, the teaching of introductory economics has not reflected these developments in the discipline. He has an article with Wendy Carlin that will be published in the near future in the Journal of Economic Perspectives entitled "What students learn in Economics 101: Time for a change"; the manuscript for this is available on the web.
Bowles has been a key force behind the Curriculum Open-access Resources in Economics (CORE) project that has developed a new textbook that is trying to be a force for change in the right direction.
Here is the link to the interview. Well worth listening to!